This seams to be a solution. I will try it. Thanks a lot.

I know this technique, but it doesn't solve my problem, since I need to use dataset2 as a filter to dataset 1

Yes. I need to find a way either join them, or use one as a filter for the other.

Dataset1 and dataset 2 have some data in common. The table I need to create only contains data in Dataset 1. But those also in Dataset 2 have to be excluded....