Anyone got any idea?

try to reapply it, if you can. I rolled it out today to 3 boxes and everything seems to be ok. Build number is actually 12.00.4439.1 for SP1 CU5

When do you get the message? What are you attempting to run/do when you get it?

What OS version are you on?

Did you try completely deactivating UAC even through the registry?

here...

I work as the only DBA for a large healthcare organization in my area. I got hired 6 months ago to fill in this position as it did not exist...