Hi,
I think, it "depends" on your database. What kind of application would you use?
If you have lots of IO, or a OLTP/OLAP, you need different drives with different speed.
The msdb, master and model database need not to be stored on very fast and expensive harddrives.
The TempDB should be stored on the fastest drive, maybe some kind of SSD. Create a drive for your user-mdf and for your user-ldf files.
Let uns know the size and some more information of your application/database.
Kind regards,
Andreas