Just to make sure I understand correctly : You want to remove the data in a particular column but without deleting the entire row and without dropping the column?
If those are all "yes" then this should do it (test in developpement first) :
This statement sets the job column to null. If this is not what you want and still need help, just come back and we'll clear it up for you.
update E SET E.job = NULL from Emp E where E.descr LIKE 'x34f%'