In-Memory OLTP is a high performance, memory-optimized engine integrated into SQL Server 2014 and designed for modern hardware trends. In-Memory OLTP allows users to move data into memory resident tables while keeping other data in traditional, disk-based table structures. For performance critical workloads, users can also migrate Transact-SQL code to natively compiled stored procedures. This can provide additional performance gains. This paper aims to help readers understand some of the common architectural patterns where In-Memory OLTP has provided significant benefits. The paper also discusses considerations for migrating applications to In-Memory OLTP.