The 13th cumulative update release for SQL Server 2008 Service Pack 3 is now available. Cumulative Update 13 contains all the hotfixes released since the initial release of SQL Server 2008 SP3.

Those who are facing severe issues with their environment, they can plan to test CU13 in test environment & then move to Production after satisfactory results.

To other, I suggest to wait for SP4 final release to deploy on your production environment, to have consolidate build.

KB Article For CU13 of SQL Server 2008 SP3

§ CU#13 KB Article: http://support.microsoft.com/kb/2880350

Previous Cumulative Update KB Articles of SQL Server 2008 SP3:

§ CU#12 KB Article: http://support.microsoft.com/kb/2863205

§ CU#11 KB Article: http://support.microsoft.com/kb/2834048

§ CU#10 KB Article: http://support.microsoft.com/kb/2814783

§ CU#9 KB Article: http://support.microsoft.com/kb/2799883

§ CU#8 KB Article: http://support.microsoft.com/kb/2771833

§ CU#7 KB Article: http://support.microsoft.com/kb/2738350

§ CU#6 KB Article: http://support.microsoft.com/kb/2715953

§ CU#5 KB Article: http://support.microsoft.com/kb/2696626

§ CU#4 KB Article: http://support.microsoft.com/kb/2673383

§ CU#3 KB Article: http://support.microsoft.com/kb/2648098

§ CU#2 KB Article: http://support.microsoft.com/kb/2633143

§ CU#1 KB Article: http://support.microsoft.com/kb/2617146

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Reference : Rohit Garg (http://mssqlfun.com/)