Those who are facing severe issues with their environment, they can plan to test CU6 in test environment & then move to Production after satisfactory results.
To other, I suggest to wait for SP3 final release to deploy on your production environment, to have consolidate build.
KB Article For CU5 of SQL Server 2008 R2 SP2
· CU#6 KB Article: http://support.microsoft.com/kb/2830140
Previous Cumulative Update KB Articles:
- CU#5 KB Article: http://support.microsoft.com/kb/2797460
- CU#4 KB Article: http://support.microsoft.com/kb/2777358
- CU#3 KB Article: http://support.microsoft.com/kb/2754552
- CU#2 KB Article: http://support.microsoft.com/kb/2740411
- CU#1 KB Article: http://support.microsoft.com/kb/2720425
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Reference : Rohit Garg (http://mssqlfun.com/)