Microsoft has released SQL Server 2008 R2 SP1 Cumulative Update 3. This is Build 10.50.2789.0, and it has 22 listed fixes. You must have SQL Server 2008 R2 SP1 installed before you can install this Cumulative Update. Especially since Microsoft added some new functionality (such as some new DMVs) to SQL Server 2008 R2 SP1, you really should be making your plans to get on the SQL Server 2008 R2 SP1 branch.
As always, I want to remind everyone that this update is only for SQL Server 2008 R2 (which is a separate major release from SQL Server 2008).
The Build matrix below makes the relationship between the builds a little more clear.
-- SQL Server 2008 R2 Builds SQL Server 2008 R2 SP1 Builds -- Build Description Build Description -- 10.50.1092 August 2009 CTP2 -- 10.50.1352 November 2009 CTP3 -- 10.50.1450 Release Candidate -- 10.50.1600 RTM -- 10.50.1702 RTM CU1 -- 10.50.1720 RTM CU2 -- 10.50.1734 RTM CU3 -- 10.50.1746 RTM CU4 -- 10.50.1753 RTM CU5 -- 10.50.1765 RTM CU6 ---> 10.50.2500 SP1 RTM -- 10.50.1777 RTM CU7 -- 10.50.1797 RTM CU8 ---> 10.50.2769 SP1 CU1 -- 10.50.1804 RTM CU9 ---> 10.50.2772 SP1 CU2 -- 10.50.1807 RTM CU10 ---> 10.50.2789 SP1 CU3
Personally, I like to try to stay current on Cumulative Updates as much as I can.