Sure you can. You'll have to use SQL Command as you data access mode in your data source configuration, and use the REPLACE function in your SQL code that you are using to retrieve data from the table.
Based on your table A, this will work just fine
SELECT A.Name,
REPLACE(A.Country, 'USA', 'Local') as Country,
A.State,
A.Zip
FROM table A A;
I hope this helps.
Cheers!